Research Peptide FAQs
Everything you need to know about our products and ordering process.
What Is Retatrutide (LY3437943)?
Retatrutide (INN: LY3437943, CAS: 2381272-89-3) is an investigational triple incretin receptor agonist developed by Eli Lilly. It is the first peptide in its class to simultaneously target three receptors: the GIP receptor (glucose-dependent insulinotropic polypeptide), the GLP-1 receptor (glucagon-like peptide-1), and the glucagon receptor.
This triple-receptor mechanism distinguishes Retatrutide from earlier-generation compounds. Semaglutide activates only GLP-1 receptors; tirzepatide activates both GLP-1 and GIP receptors. Retatrutide's additional glucagon receptor agonism adds a third dimension to its metabolic research profile, making it the subject of active Phase 3 clinical investigation.
Our Retatrutide is supplied as lyophilized powder in a sterile vial, tested at ≥98% purity by HPLC with mass spectrometry identity confirmation. A Certificate of Analysis (CoA) is available for every batch. For in-vitro research and laboratory use only. Not for human consumption.